working capacity calculation for the equipment in pharmaceuticals
1. Identify Equipment Capacity from URS/Manual Check manufacturer’s datasheet or URS (User Requirement Specification) – it gives total capacity/volume/weight handling capacity (e.g., blender 500 L, FBD 60 kg, compression machine 40 stations, etc.). 2. Apply Working Capacity Factor For GMP, we never use 100% of design capacity because of safety, mixing efficiency, and process performance. Typical industry thumb rules: Blender (double cone, V-blender, bin blender): 50–70% of gross volume Fluid Bed Dryer (FBD): 40–60% of rated volume (depends on bulk density, airflow) Granulator / RMG: 60–80% of total volume Compression Machine: Capacity depends on turret speed × no. of stations × tablet weight Coating Pan: 60–70% of pan volume Autoclave: 70–80% load of chamber volume (based on load configuration) 3. Calculate Working Capacity Formula (for volume-based equipment): Working Capacity (kg) = Gross Volume (L) × Bulk De...
